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Special Focus Meeting

β-hydroxybutyrate (BHB)
in applied metabolic nutrition

9 June 2026
Afternoon session from 15:00 CEST
Spain (On-site) · Hybrid Online
About SIAN

Scientific Institute for Advanced Nutrition

The Scientific Institute for Advanced Nutrition is an independent body committed to advancing evidence-based metabolic nutrition through rigorous science and clinical translation.

Evidence

Generating and evaluating high-quality clinical evidence for metabolic nutrition interventions.

Quality

Upholding rigorous scientific and manufacturing standards across research and product development.

Clinical Impact

Translating bench science into actionable clinical guidance for healthcare professionals.

Transparency

Maintaining full disclosure of conflicts, funding sources, and scientific methodology.

About the Meeting

BHB in Applied Metabolic Nutrition

Scientific Rationale

Beta-hydroxybutyrate (BHB) has emerged as a molecule of significant clinical interest beyond its role as an energy substrate. This meeting convenes leading investigators to evaluate the current evidence base, identify knowledge gaps, and set priorities for rigorous clinical research in metabolic nutrition.

Intended Audience

  • Clinicians and metabolic medicine specialists
  • Nutrition scientists and researchers
  • Regulatory affairs professionals
  • Industry leaders in metabolic health
  • Academic investigators in ketone biology

Key Themes

  • Standards and worldwide regulation of BHB
  • Innovation in supply, production, and natural fermented BHB
  • Clinical applications in migraine, diabetes, and mechanism of action
  • Future science: brain function, ageing, and BHB signalling
Scientific Program

Program at a Glance

9 June 2026 · Afternoon Session · 15:00 CEST

KEYNOTE

Past, Present and Future: The BHB Journey

Opening keynote tracing the historical development of BHB research to current clinical applications and future directions.

REGULATORY

Session 1: Standards & Worldwide Regulation

Clinical applications, regulatory vision, and the global regulatory landscape for BHB products.

INDUSTRY

Session 2: Innovation in BHB Supply & Production

Review of BHB types (salts, esters, fermented forms) and emerging natural fermented BHB technologies.

REVIEW

Major Success: BHB in Practice

Real-world translation of BHB from bench to bedside in applied nutrition practice.

CLINICAL

Session 3: Clinical Applications

Cutting-edge evidence in migraine, diabetes, and mechanisms of action linking biochemical insights to real-world practice.

FUTURE SCIENCE

Session 4: Brain Function, Ageing & BHB Signalling

Frontier research on brain energy metabolism, epigenetic effects, inflammatory modulation, and cellular resilience.

Faculty

Meeting Faculty

The Scientific Institute for Advanced Nutrition is proud to be guided by a world-class faculty of clinical pioneers, regulatory experts, and breakthrough innovators. Our leadership spans three continents—bringing together deep expertise from Europe, Japan, and the United States to advance thinking and standards for Beta-hydroxybutyrate (BHB) and applied metabolic nutrition.

Meeting Chairs

RL

Dr. R. Littlewood, MD

Europe Chair

Medical Doctor; Inventor of Klario. Clinical applications & regulatory vision for BHB.

JT

Dr. J. Tsubota

Japan Chair

International metabolic nutrition.

GM

Gary Millet

USA Chair

Global pioneer in production & application of BHB.

Session Faculty

GM

G. Myers

CEO, Flow Health Science

Global BHB regulatory landscape.

DR

Prof. Dr. D. Russell-Jones

United Kingdom

BHB evidence in diabetes management.

ML

Prof. Dr. M. Laffan

United Kingdom

BHB mechanism of action.

Speakers

Confirmed Speakers

Gary Milllet (US)
Global pioneer in invention, protection, application of BHB
Rob Rogers (US)
Leader in high-impact BHB use & product development
Prof Dr D Russell-Jones (UK)
Clinical expert in diabetes, including BHB applications
Prof Dr M Laffan (UK)
Leader in defined BHB translational science
Dr J Tsubota (JP)
Expert in microbial production of BHB
Dr R Littlewood (UK)
Inventor of Klario (BHB product for diabetes hypos)
Venue & Format

How to Attend

In-Person

Location
Spain (exact venue to be confirmed)
Date
9 June 2026, afternoon session
Time Zone
CEST (Central European Summer Time, UTC+2) — Start: 15:00 CEST
Access
By invitation, limited capacity

Online Participation

Format
Live-streamed via secure conference platform
Interaction
Full participation including Q&A
Time Zones
Optimised for Europe, with accessibility for Japan (evening) and US East Coast (morning)
Access
By registration; connection details provided upon confirmation
Register

Register Your Interest

This Special Focus Meeting is by invitation with limited capacity. Complete the form below to register your interest. You will receive further details including program updates, venue logistics, and formal invitations as they become available.